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The Concern: A Rare Vision Condition (NA-AION) Some early reports suggested a link between GLP-1 drugs and non-arteritic anterior ischemic optic neuropathy (NA-AION)

Until clinical trials are completed, taking oral tirzepatide (even if it were available) would be a gamble

Black widow spider alpha-latrotoxin: a presynaptic neurotoxin that shares structural homology with the glucagon-like peptide-1 family of insulin secretagogic hormones

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However, none of these other factors had a statistically significant correlation with iAUC glucose or GLP-1