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How effective are naltrexone and bupropion for weight loss
10.3390/nu10060693 98
Similarly, the dual GLP-1R and GIP agonist tirzepatide promoted the intake of standard rodent chow at the expense of a high-fat diet in mice, suggesting a preferential shift toward less energy-dense foods (Geisler et al., 2023)
The headline figure that got attention: a 15.9% non-placebo-adjusted weight loss at 32 weeks on 2.4 mg weekly dosing, with no plateau observed at that timepoint
Start: Begin at ~250 mcg once daily (some start at 100 mcg) to gauge tolerability for nausea and flushing
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