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Eur J Obstet Gynecol Reprod Biol 1991;42:163-4
Proc Natl Acad Sci USA (2006) 103(37):1386671
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Following either local secretion or systemic circulation to target tissues, IGF-1 primarily exerts its biological effects through binding to the IGF-1 receptor (IGF-1R), with minimal interaction occurring through the insulin receptor (IR) (Figure 2) (Werner, 2023)
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