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Bacterial ghosts (BGs) are empty bacterial shells obtained from Gram-negative bacteria such as E
For example, EVs secreted by cerulein-stimulated acinar cells delivered miR-183-5p, which downregulated forkhead box protein O1, promoted M1 macrophage polarization, and increased macrophage infiltration into the pancreas, ultimately leading to acinar cell injury and trypsinogen activation
Cesta CE, Rotem R, Bateman BT et al (2024) Safety of GLP-1 receptor agonists and other second-line antidiabetics in early pregnancy
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Level of Evidence Summary: Diabetic Peripheral Neuropathy: Moderate ([1][6]) Peripheral Neuropathic Pain (General): Moderate[11] Fibromyalgia: Low to Moderate[7][8][9] Central Sensitization/Nociplastic Pain: Low to Moderate (Strong mechanistic rationale
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