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Safety data in pregnancy remains limited
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Cancer Res (2004) 64(24):91318.10.1158/0008-5472.CAN-04-0283 52 OkamuraTSinghSBuolamwiniJHaysteadTFriedmanHBignerDet alTyrosine phosphorylation of the human glutathione S-transferase P1 by epidermal growth factor receptor
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An open-label study (n=42) found that IV NAC (50 mg/kg) combined with oral NAC (500 mg twice daily) for 3 months increased brain glutathione levels (measured by MRS), increased dopamine transporter binding (measured by DaTscan), and improved UPDRS motor scores (Monti et al., PLoS One, 2016) [53]
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