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Other benefits, such as reduced inflammation and improved digestion, often become more apparent with consistent use over time

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It is also important to rule out unrelated medical causes of fatigue, particularly if the tiredness feels disproportionate to the degree of appetite suppression or gastrointestinal symptoms experienced

Niacin can produce a variety of GI effects, such as nausea/vomiting, abdominal pain, diarrhea, bloating, dyspepsia, or flatulence, when taken in large doses