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Note: doses as low as 1.2 g daily in humans might confer a pro-oxidant effect, lowering GSH and increasing the GSH/GSSG ratio
Gastrointestinal symptoms: alteration in bowel motility, such as mild diarrhea or constipation, and loss of bladder or bowel control
The marked reduction in GSH, CAT, and SOD confirmed that hepatocytes under statin pressure suffered weakened antioxidant defenses [27, 28]
In the recurrence group, under the treatment pressure of NAC, 53 genes (Group 4) were upregulated and 54 genes (Group 7) were downregulated