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Because of those different receptors, they can stimulate different volumes of release, over different periods of time
However, metformin is not appropriate for people with certain other medical conditions, such as kidney disease, congestive heart failure, metabolic acidosis, and liver issues
Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance
I have always thought, along with other colleagues for a long time, that you can start identifying groups that have lived with obesity for a very long period of time and they would somehow present differently metabolically and so on, and it would give us an understanding of what treatments would be better for someone, let's say, with long-term obesity versus someone with short-term obesity
PMID: 27037767
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