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While GLP-1 is widely known and a solid starting point, the science has moved well beyond it

Endocr Rev 5(1):76127 Zhou P, Baumgarten SC, Wu Y, Bennett J, Winston N, Hirshfeld-Cytron J et al (2013) IGF-I signaling is essential for FSH stimulation of AKT and steroidogenic genes in granulosa cells

Even then, many prefer to stay on a lower maintenance dose rather than stop entirely

Its pentadecapeptide structure and stability profile help provide consistent readouts across varied in-vitro systems

Other evidence suggests the L-cells located in the proximal jejunum are sufficient to account for the early-phase secretion through direct contact with luminal nutrients