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Visual Format: Side-effect and safety matrix Key Labels: Topical irritation, allergic reaction, formulation sensitivity, wound-care context, injectable route, limited safety data, peptide impurities, immunogenicity risk Suggested Layout: Create a three-column matrix: Topical products, Wound-care study context, and Injectable or compounded preparations. Under each column, list route-specific safety considerations using short, neutral labels

Most research has focused on fat metabolism, while separate animal studies have also looked at joints and cartilage

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A SYBR Premix Ex Taq II (Tli RNaseH Plus) Kit was used to perform qRT-PCR in technical triplicate on a StepOnePlus Real-time PCR System (Applied Biosystems, USA) following the manufacturers instructions