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The intrinsic pathway can be triggered either as a result of mPTP opening, or activation of the proapoptotic proteins of the B-cell lymphoma 2 (Bcl-2) family, Bax and Bak [192] after the removal of the block of antiapoptotic proteins Bcl-2 and Bcl-XL [193]

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In a review article published in the journal Antioxidants , researchers at the University of Auckland, New Zealand, have discussed potential cataract treatment strategies that utilize endogenous molecular machinery of the eye lens to increase the level of antioxidant glutathione in different lens regions

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