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The existing body of literature helps researchers understand the potential goals of multi-peptide study designs

McLelland, G

One proposal is that hypofunction of NMDA receptors (NMDAR) located on inhibitory GABA inter-neurons leads to reduced activity of these inter-neurons, resulting in increased pyramidal glutamatergic neurotransmission and the diverse symptoms occurring in acute psychosis [3]

In our bulk RNAseq data, we noted that pathways such as oxidative phosphorylation and electron transport chain were significantly downregulated ( Supplementary Figures 5B, C )

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