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The minimal side effects observed were mainly flares of MCAS-driven symptoms in response to initial dosing, which were easily managed with extra doses of H1/H2 receptor blockers
Studies using the mouse Glp1r promoter to drive expression of a fluorescent reporter protein reveal Glp1r expression in the antral area of the stomach (near the gastric pylorus) as a fibrous signal that does not overlap with smooth muscle -actin (SMA) (Richards et al., 2014)
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