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NCT06239116

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The peptide normalized lower esophageal sphincter pressure in rat models of GERD, suggesting potential for addressing underlying pathophysiology rather than merely symptom suppression

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It is proposed to work by binding GHRH receptors on pituitary somatotroph cells, prompting the pituitary to synthesize and release its own growth hormone in a pulsatile pattern, with the body's somatostatin feedback loop still intact so the effect is self-limiting rather than a constant hormone flood

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10.1159/000346968 19 EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies) (2015)

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