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GLP-1RAs stimulate insulin secretion and suppress glucagon secretion, which may modify cardiac energy metabolism in T2DM patients [103]

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This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription 27,99 / 30 days cancel any time Subscribe to this journal Receive 12 digital issues and online access to articles 121,22 per year only 10,10 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

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Any change in the COMT gene may cause the body to be slower to deactivate and expel these chemicals, which can lead to changes in stress reactions

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(Not just those with the chronic diseases that GLP-1s treat.) Below, health experts discuss the known benefits of GLP-1s, whether theyre really longevity drugs, and current concerns about people taking these medications to extend their healthy years

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